St. Margaret of Antioch is one of the early virgin martyrs of the church and one of the Fourteen Holy Helpers.

Margaret was the daughter of a pagan priest and her mother died during childbirth. Margaret was raised and nursed by a Christian woman. She soon embraced Christianity and consecrated her virginity to God. Her father disowned her for her faith.

Olybrius, a Governor in the Roman Empire asked to marry her and demanded that she renounce her faith. She refused and was tortured.

During her torture, various miracles occurred, including defeating a Satan in the form of a dragon. Margaret was eventually beheaded.

Margaret is one of the saints that spoke to St. Joan of Arc. She is also one of the Fourteen Holy Helpers who are a group of saints venerated together in Catholic tradition because their intercession is believed to be particularly effective against specific diseases and dangers. Each saint is invoked for aid regarding particular ailments or needs. The Fourteen Holy Helpers are: Acacius, Barbara, Blaise, Catherine of Alexandria, Christopher, Cyriacus, Denis, Erasmus of Formia, Eustace, George, Giles, Margaret of Antioch, Pantaleon, and Vitus.